One of the great things about WordPress, is that you can just run it as it is, or if you want it (and your website, and you) to be Great, you can find lots of ways to tweak it.
These are the details of things i do when installing and configuring WordPress. They were collected from what i have learned over the past 5 years of working with WordPress, and the past 20 years of making websites.
All websites are different, and all people are different! Also, if you are just starting out, this may all seem overwhelming. Just take this as a map of the entire territory, and see what works for you.
You don't have to do everything in these lists. You will learn as you go — as you find things that you want to do!